high sensitivity c–reactive protein and im-munoglobulin g against chlamydia pneumo-niae and chlamydial heat shock protein-60 in ischemic heart disease

Authors

abdollah jafarzadeh

department of immunology ali esmaeeli-nadimi

department of cardiology mehdi shariati

department of histology, rafsanjan university of medical sciences, rafsanjan, iran

abstract

background: inflammation and infectious agents such as chlamydia pneumoniae have been associated with cardiovascular disease. objective: to evaluate the serum high sensitivity c - reactive protein (hs-crp) and antibodies against chlamydia pneumoniae and chlamydial heat shock protein-60 (cp-hsp60) in patients with ischemic heart disease (ihd). methods: 62 patients with ihd having either acute myocardial infarction (ami; n=31) or unstable an-gina (ua; n=31) and 31 sex- and age- matched healthy subjects as a control group were en-rolled in this study. serum samples of participants were tested for the presence of hs-crp and antibodies against c. pneumoniae and cp-hsp60 using elisa method. results: the sero-prevalence of anti-c. pneumoniae antibody in ami group (93.5%) or ua group (90.3%) was significantly higher than the control group (61.3%; p

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Journal title:
iranian journal of immunology

جلد ۵، شماره ۱، صفحات ۵۱-۵۶

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